Simultaneous Quantification and Pharmacokinetic Study of Five Homologs of Dalbavancin in Rat Plasma Using UHPLC-MS/MS

Simultaneous Quantification and Pharmacokinetic Study of Five Homologs of Dalbavancin in Rat Plasma Using UHPLC-MS/MS

Dalbavancin is a novel semisynthetic glycopeptide antibiotic that comprises multiple homologs and isomers of similar polarities. However, pharmacokinetic studies have only analyzed the primary components of dalbavancin, namely B<sub>0</sub> and B<sub>1</sub>. In this study, a...

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Bibliographic Details
Main Authors: Difeng Zhu, Li Ping, Yawen Hong, Jiale Shen, Qinjie Weng, Qiaojun He
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
dalbavancin
homolog
isomer
UHPLC-MS/MS
rat plasma
pharmacokinetics study
Online Access:https://www.mdpi.com/1420-3049/25/18/4100

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