Dengzhan Shengmai capsules and their active component scutellarin prevent cognitive decline in APP/PS1 mice by accelerating Aβ aggregation and reducing oligomers formation

Dengzhan Shengmai capsules and their active component scutellarin prevent cognitive decline in APP/PS1 mice by accelerating Aβ aggregation and reducing oligomers formation

There is currently no effective treatment to prevent the progress of Alzheimer’s disease (AD). The traditional Chinese herbs Dengzhan Shengmai (DZSM) capsules and their active component scutellarin possess multiple effects and are clinically used for the treatment of cerebrovascular diseases. Scutel...

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Bibliographic Details
Main Authors: Shujuan Zhang, Jianxiang Zhang, Dongfeng Wei, Haiting An, Wei Liu, Yihui Lai, Te Yang, Wen Shao, Yaping Huang, Lei Wang, Fei Dou, Dantao Peng, Zhanjun Zhang
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Alzheimer’s disease
DZSM capsules
Scutellarin
Aβ aggregation
Fibrils
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219353041

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