Marine Natural Products from Microalgae: An -Omics Overview
Over the last decade, genome sequences and other -omics datasets have been produced for a wide range of microalgae, and several others are on the way. Marine microalgae possess distinct and unique metabolic pathways, and can potentially produce specific secondary metabolites with biological activity...
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doaj-988c230b3796476a81c5891134fc1fff2020-11-25T01:36:36ZengMDPI AGMarine Drugs1660-33972019-05-0117526910.3390/md17050269md17050269Marine Natural Products from Microalgae: An -Omics OverviewChiara Lauritano0Maria Immacolata Ferrante1Alessandra Rogato2Marine Biotechnology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, ItalyIntegrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, ItalyIntegrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, ItalyOver the last decade, genome sequences and other -omics datasets have been produced for a wide range of microalgae, and several others are on the way. Marine microalgae possess distinct and unique metabolic pathways, and can potentially produce specific secondary metabolites with biological activity (e.g., antipredator, allelopathic, antiproliferative, cytotoxic, anticancer, photoprotective, as well as anti-infective and antifouling activities). Because microalgae are very diverse, and adapted to a broad variety of environmental conditions, the chances to find novel and unexplored bioactive metabolites with properties of interest for biotechnological and biomedical applications are high. This review presents a comprehensive overview of the current efforts and of the available solutions to produce, explore and exploit -omics datasets, with the aim of identifying species and strains with the highest potential for the identification of novel marine natural products. In addition, funding efforts for the implementation of marine microalgal -omics resources and future perspectives are presented as well.https://www.mdpi.com/1660-3397/17/5/269marine microalgaemarine natural products (MNPs)bioactive compoundsblue biotechnologygenomicstranscriptomicsproteomicsmetabolomicsgenetic engineeringbioinformatics |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chiara Lauritano Maria Immacolata Ferrante Alessandra Rogato |
spellingShingle |
Chiara Lauritano Maria Immacolata Ferrante Alessandra Rogato Marine Natural Products from Microalgae: An -Omics Overview Marine Drugs marine microalgae marine natural products (MNPs) bioactive compounds blue biotechnology genomics transcriptomics proteomics metabolomics genetic engineering bioinformatics |
author_facet |
Chiara Lauritano Maria Immacolata Ferrante Alessandra Rogato |
author_sort |
Chiara Lauritano |
title |
Marine Natural Products from Microalgae: An -Omics Overview |
title_short |
Marine Natural Products from Microalgae: An -Omics Overview |
title_full |
Marine Natural Products from Microalgae: An -Omics Overview |
title_fullStr |
Marine Natural Products from Microalgae: An -Omics Overview |
title_full_unstemmed |
Marine Natural Products from Microalgae: An -Omics Overview |
title_sort |
marine natural products from microalgae: an -omics overview |
publisher |
MDPI AG |
series |
Marine Drugs |
issn |
1660-3397 |
publishDate |
2019-05-01 |
description |
Over the last decade, genome sequences and other -omics datasets have been produced for a wide range of microalgae, and several others are on the way. Marine microalgae possess distinct and unique metabolic pathways, and can potentially produce specific secondary metabolites with biological activity (e.g., antipredator, allelopathic, antiproliferative, cytotoxic, anticancer, photoprotective, as well as anti-infective and antifouling activities). Because microalgae are very diverse, and adapted to a broad variety of environmental conditions, the chances to find novel and unexplored bioactive metabolites with properties of interest for biotechnological and biomedical applications are high. This review presents a comprehensive overview of the current efforts and of the available solutions to produce, explore and exploit -omics datasets, with the aim of identifying species and strains with the highest potential for the identification of novel marine natural products. In addition, funding efforts for the implementation of marine microalgal -omics resources and future perspectives are presented as well. |
topic |
marine microalgae marine natural products (MNPs) bioactive compounds blue biotechnology genomics transcriptomics proteomics metabolomics genetic engineering bioinformatics |
url |
https://www.mdpi.com/1660-3397/17/5/269 |
work_keys_str_mv |
AT chiaralauritano marinenaturalproductsfrommicroalgaeanomicsoverview AT mariaimmacolataferrante marinenaturalproductsfrommicroalgaeanomicsoverview AT alessandrarogato marinenaturalproductsfrommicroalgaeanomicsoverview |
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