Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study.
AIM:To evaluate the caries prevalence and related variables in Type 1 diabetic and non-diabetic children and among the diabetic children according to their metabolic status. METHODS:Sixty-eight diabetic and 136 non-diabetic children, matching by gender and age (4-14 years) were enrolled. The diabeti...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5708823?pdf=render |
id |
doaj-988cc8074de74a4598f2c666af142aaa |
---|---|
record_format |
Article |
spelling |
doaj-988cc8074de74a4598f2c666af142aaa2020-11-25T01:54:09ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-011211e018845110.1371/journal.pone.0188451Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study.Stefano LaiMaria Grazia CagettiFabio CoccoDina CosselluGianfranco MeloniGuglielmo CampusPeter LingströmAIM:To evaluate the caries prevalence and related variables in Type 1 diabetic and non-diabetic children and among the diabetic children according to their metabolic status. METHODS:Sixty-eight diabetic and 136 non-diabetic children, matching by gender and age (4-14 years) were enrolled. The diabetic children were divided: a) 20 children in good metabolic control (Hb1ac≤7.5) and b) 48 children in bad metabolic control (Hb1ac>7.5). Dietary and oral hygiene habits were investigated. Caries status was registered using the International Caries Detection and Assessment System. Oral microflora was analysed using the checkerboard DNA-DNA hybridisation method. Plaque acidogenicity was recorded after a sucrose rinse. RESULTS:Sugared beverage and snack intake was higher in diabetic group compared to non-diabetic group (p = 0.03 and p = 0.04, respectively) and in subjects in bad metabolic control (p = 0.03 and p<0.01, respectively). Oral hygiene habits were similar, except for the use of fluoridated adjuvants, higher in non-diabetic children (p = 0.04). No statistically significant differences were observed regarding caries figures, but a higher number of caries free subjects was found in diabetic subjects in good metabolic control (p<0.01). Significant difference for the main cariogenic bacteria was found between diabetic and non-diabetic subjects (p<0.05). The pH values showed statistically significant differences between diabetic and non-diabetic subjects and between diabetic subjects in good and bad metabolic control (p<0.01). CONCLUSIONS:Diabetic children in good metabolic control might even be considered at low caries risk, while those in bad metabolic control showed an oral environment prone to a high caries risk.http://europepmc.org/articles/PMC5708823?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Stefano Lai Maria Grazia Cagetti Fabio Cocco Dina Cossellu Gianfranco Meloni Guglielmo Campus Peter Lingström |
spellingShingle |
Stefano Lai Maria Grazia Cagetti Fabio Cocco Dina Cossellu Gianfranco Meloni Guglielmo Campus Peter Lingström Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study. PLoS ONE |
author_facet |
Stefano Lai Maria Grazia Cagetti Fabio Cocco Dina Cossellu Gianfranco Meloni Guglielmo Campus Peter Lingström |
author_sort |
Stefano Lai |
title |
Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study. |
title_short |
Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study. |
title_full |
Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study. |
title_fullStr |
Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study. |
title_full_unstemmed |
Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study. |
title_sort |
evaluation of the difference in caries experience in diabetic and non-diabetic children-a case control study. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2017-01-01 |
description |
AIM:To evaluate the caries prevalence and related variables in Type 1 diabetic and non-diabetic children and among the diabetic children according to their metabolic status. METHODS:Sixty-eight diabetic and 136 non-diabetic children, matching by gender and age (4-14 years) were enrolled. The diabetic children were divided: a) 20 children in good metabolic control (Hb1ac≤7.5) and b) 48 children in bad metabolic control (Hb1ac>7.5). Dietary and oral hygiene habits were investigated. Caries status was registered using the International Caries Detection and Assessment System. Oral microflora was analysed using the checkerboard DNA-DNA hybridisation method. Plaque acidogenicity was recorded after a sucrose rinse. RESULTS:Sugared beverage and snack intake was higher in diabetic group compared to non-diabetic group (p = 0.03 and p = 0.04, respectively) and in subjects in bad metabolic control (p = 0.03 and p<0.01, respectively). Oral hygiene habits were similar, except for the use of fluoridated adjuvants, higher in non-diabetic children (p = 0.04). No statistically significant differences were observed regarding caries figures, but a higher number of caries free subjects was found in diabetic subjects in good metabolic control (p<0.01). Significant difference for the main cariogenic bacteria was found between diabetic and non-diabetic subjects (p<0.05). The pH values showed statistically significant differences between diabetic and non-diabetic subjects and between diabetic subjects in good and bad metabolic control (p<0.01). CONCLUSIONS:Diabetic children in good metabolic control might even be considered at low caries risk, while those in bad metabolic control showed an oral environment prone to a high caries risk. |
url |
http://europepmc.org/articles/PMC5708823?pdf=render |
work_keys_str_mv |
AT stefanolai evaluationofthedifferenceincariesexperienceindiabeticandnondiabeticchildrenacasecontrolstudy AT mariagraziacagetti evaluationofthedifferenceincariesexperienceindiabeticandnondiabeticchildrenacasecontrolstudy AT fabiococco evaluationofthedifferenceincariesexperienceindiabeticandnondiabeticchildrenacasecontrolstudy AT dinacossellu evaluationofthedifferenceincariesexperienceindiabeticandnondiabeticchildrenacasecontrolstudy AT gianfrancomeloni evaluationofthedifferenceincariesexperienceindiabeticandnondiabeticchildrenacasecontrolstudy AT guglielmocampus evaluationofthedifferenceincariesexperienceindiabeticandnondiabeticchildrenacasecontrolstudy AT peterlingstrom evaluationofthedifferenceincariesexperienceindiabeticandnondiabeticchildrenacasecontrolstudy |
_version_ |
1724988811676483584 |