The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis

The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis

Toll-like receptor 4 (TLR4) signal activation of macrophages can lead to endotoxin-induced uveitis (EIU). Previously, our research group has demonstrated a higher expression of TLR4 <em>in vivo</em> during EIU than normal. In this study, we analyzed levels of peritoneal m...

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Bibliographic Details
Main Authors: Shuo Yang, Hong Lu, Jing Wang, Xin Qi, Xuhui Liu, Xiaolong Zhang
Format: Article
Language:English
Published: MDPI AG 2012-06-01
Series:International Journal of Molecular Sciences
Subjects:
Toll-like receptor 4
mice peritoneal macrophage
endotoxin-induced uveitis
cytokine
Online Access:http://www.mdpi.com/1422-0067/13/6/7508
Description
Summary:Toll-like receptor 4 (TLR4) signal activation of macrophages can lead to endotoxin-induced uveitis (EIU). Previously, our research group has demonstrated a higher expression of TLR4 <em>in vivo</em> during EIU than normal. In this study, we analyzed levels of peritoneal macrophage cytokines from C3H/HeN mice with LPS stimulation <em>in vitro</em> to elucidate the effect of TLR4 on cytokines during EIU.
ISSN:1422-0067

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