The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis

The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis

Toll-like receptor 4 (TLR4) signal activation of macrophages can lead to endotoxin-induced uveitis (EIU). Previously, our research group has demonstrated a higher expression of TLR4 <em>in vivo</em> during EIU than normal. In this study, we analyzed levels of peritoneal m...

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Bibliographic Details
Main Authors: Shuo Yang, Hong Lu, Jing Wang, Xin Qi, Xuhui Liu, Xiaolong Zhang
Format: Article
Language:English
Published: MDPI AG 2012-06-01
Series:International Journal of Molecular Sciences
Subjects:
Toll-like receptor 4
mice peritoneal macrophage
endotoxin-induced uveitis
cytokine
Online Access:http://www.mdpi.com/1422-0067/13/6/7508
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spelling doaj-9897c308bf3542ebbd40f5b8391f00a32020-11-25T00:27:33ZengMDPI AGInternational Journal of Molecular Sciences1422-00672012-06-011367508752010.3390/ijms13067508The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced UveitisShuo YangHong LuJing WangXin QiXuhui LiuXiaolong ZhangToll-like receptor 4 (TLR4) signal activation of macrophages can lead to endotoxin-induced uveitis (EIU). Previously, our research group has demonstrated a higher expression of TLR4 <em>in vivo</em> during EIU than normal. In this study, we analyzed levels of peritoneal macrophage cytokines from C3H/HeN mice with LPS stimulation <em>in vitro</em> to elucidate the effect of TLR4 on cytokines during EIU.http://www.mdpi.com/1422-0067/13/6/7508Toll-like receptor 4mice peritoneal macrophageendotoxin-induced uveitiscytokine
collection DOAJ
language English
format Article
sources DOAJ
author Shuo Yang
Hong Lu
Jing Wang
Xin Qi
Xuhui Liu
Xiaolong Zhang
spellingShingle Shuo Yang
Hong Lu
Jing Wang
Xin Qi
Xuhui Liu
Xiaolong Zhang
The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis
International Journal of Molecular Sciences
Toll-like receptor 4
mice peritoneal macrophage
endotoxin-induced uveitis
cytokine
author_facet Shuo Yang
Hong Lu
Jing Wang
Xin Qi
Xuhui Liu
Xiaolong Zhang
author_sort Shuo Yang
title The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis
title_short The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis
title_full The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis
title_fullStr The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis
title_full_unstemmed The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis
title_sort effect of toll-like receptor 4 on macrophage cytokines during endotoxin induced uveitis
publisher MDPI AG
series International Journal of Molecular Sciences
issn 1422-0067
publishDate 2012-06-01
description Toll-like receptor 4 (TLR4) signal activation of macrophages can lead to endotoxin-induced uveitis (EIU). Previously, our research group has demonstrated a higher expression of TLR4 <em>in vivo</em> during EIU than normal. In this study, we analyzed levels of peritoneal macrophage cytokines from C3H/HeN mice with LPS stimulation <em>in vitro</em> to elucidate the effect of TLR4 on cytokines during EIU.
topic Toll-like receptor 4
mice peritoneal macrophage
endotoxin-induced uveitis
cytokine
url http://www.mdpi.com/1422-0067/13/6/7508
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