Regulation of classic and alternative bile acid synthesis in hypercholesterolemic rabbits: effects of cholesterol feeding and bile acid depletion

Regulation of classic and alternative bile acid synthesis in hypercholesterolemic rabbits: effects of cholesterol feeding and bile acid depletion

The effect of cholesterol feeding (3 g/day) on bile acid synthesis was examined in 10 New Zealand white rabbits (NZW), 8 Watanabe heterozygous and 10 homozygous rabbits with partial and complete deficiencies of LDL receptors. After 10 days of cholesterol feeding, bile fistulas were constructed and b...

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Bibliographic Details
Main Authors: Guorong Xu, Gerald Salen, Sarah Shefer, G. Stephen Tint, Lien B. Nguyen, Thomas T. Parker, Thomas S. Chen, Jeremy Roberts, Xianglin Kong, David Greenblatt
Format: Article
Language:English
Published: Elsevier 1998-08-01
Series:Journal of Lipid Research
Subjects:
LDL receptor
bile fistula
cholesterol 7α-hydroxylase
cholic acid
HMG-CoA reductase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520321908

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http://www.sciencedirect.com/science/article/pii/S0022227520321908

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