FTIR characterization of Sahara honey and propolis and evaluation of its anticandidal potentials
Antifungal of bee products have been shown to be protective against microbial biofilms invasion Sahara honey and propolis were applied as an antimicrobial in treatment for many infections in Algeria. In this study, Fourier transform infrared spectroscopy (FTIR) analysis was utilized to characterize...
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doaj-98a57e7535ce4de79a38322449c827572021-09-06T19:41:20ZengSciendoActa Scientifica Naturalis2367-51442020-11-0173465710.2478/asn-2020-0032FTIR characterization of Sahara honey and propolis and evaluation of its anticandidal potentialsAhmed Moussa0Amirat Mokhtar1Aissat Saad2Aissa Mohamed Amine3Khiati Baghdad4Institute of Veterinary Sciences, University Ibn-Khaldoun of Tiaret, AlgeriaInstitute of Veterinary Sciences, University Ibn-Khaldoun of Tiaret, AlgeriaInstitute of Veterinary Sciences, University Ibn-Khaldoun of Tiaret, AlgeriaInstitute of Veterinary Sciences, University Ibn-Khaldoun of Tiaret, AlgeriaInstitute of Veterinary Sciences, University Ibn-Khaldoun of Tiaret, AlgeriaAntifungal of bee products have been shown to be protective against microbial biofilms invasion Sahara honey and propolis were applied as an antimicrobial in treatment for many infections in Algeria. In this study, Fourier transform infrared spectroscopy (FTIR) analysis was utilized to characterize the chemical structures and functional groups. In addition, in this study, we determined the anti-candida activity of honey used alone or in combination with propolis. Proteins, carbohydrates, carboxylic acids, free amino acids, cellulose and lipids, ketones and phenol compounds were identified by FTIR analysis. Combination of Sahara honey and propolis increased antifungal efficacy, compared to compounds tested alone. Propolis increased the anti-candidal effect of Sahara honey. In addition, the treatment of Sahara honey and Propolis-Sahara honey catheters with a Candida albicans biofilms reduced biofilm formation after 24 and 48-h exposure period. The results provide evidence that honey/propolis combination may help in designing a more potent novel, natural antibiofilm blend at sufficiently low concentrations in medical domain.https://doi.org/10.2478/asn-2020-0032ftircandida albicanshoneypropolisantibiofilm activity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ahmed Moussa Amirat Mokhtar Aissat Saad Aissa Mohamed Amine Khiati Baghdad |
spellingShingle |
Ahmed Moussa Amirat Mokhtar Aissat Saad Aissa Mohamed Amine Khiati Baghdad FTIR characterization of Sahara honey and propolis and evaluation of its anticandidal potentials Acta Scientifica Naturalis ftir candida albicans honey propolis antibiofilm activity |
author_facet |
Ahmed Moussa Amirat Mokhtar Aissat Saad Aissa Mohamed Amine Khiati Baghdad |
author_sort |
Ahmed Moussa |
title |
FTIR characterization of Sahara honey and propolis and evaluation of its anticandidal potentials |
title_short |
FTIR characterization of Sahara honey and propolis and evaluation of its anticandidal potentials |
title_full |
FTIR characterization of Sahara honey and propolis and evaluation of its anticandidal potentials |
title_fullStr |
FTIR characterization of Sahara honey and propolis and evaluation of its anticandidal potentials |
title_full_unstemmed |
FTIR characterization of Sahara honey and propolis and evaluation of its anticandidal potentials |
title_sort |
ftir characterization of sahara honey and propolis and evaluation of its anticandidal potentials |
publisher |
Sciendo |
series |
Acta Scientifica Naturalis |
issn |
2367-5144 |
publishDate |
2020-11-01 |
description |
Antifungal of bee products have been shown to be protective against microbial biofilms invasion Sahara honey and propolis were applied as an antimicrobial in treatment for many infections in Algeria. In this study, Fourier transform infrared spectroscopy (FTIR) analysis was utilized to characterize the chemical structures and functional groups. In addition, in this study, we determined the anti-candida activity of honey used alone or in combination with propolis. Proteins, carbohydrates, carboxylic acids, free amino acids, cellulose and lipids, ketones and phenol compounds were identified by FTIR analysis. Combination of Sahara honey and propolis increased antifungal efficacy, compared to compounds tested alone. Propolis increased the anti-candidal effect of Sahara honey. In addition, the treatment of Sahara honey and Propolis-Sahara honey catheters with a Candida albicans biofilms reduced biofilm formation after 24 and 48-h exposure period. The results provide evidence that honey/propolis combination may help in designing a more potent novel, natural antibiofilm blend at sufficiently low concentrations in medical domain. |
topic |
ftir candida albicans honey propolis antibiofilm activity |
url |
https://doi.org/10.2478/asn-2020-0032 |
work_keys_str_mv |
AT ahmedmoussa ftircharacterizationofsaharahoneyandpropolisandevaluationofitsanticandidalpotentials AT amiratmokhtar ftircharacterizationofsaharahoneyandpropolisandevaluationofitsanticandidalpotentials AT aissatsaad ftircharacterizationofsaharahoneyandpropolisandevaluationofitsanticandidalpotentials AT aissamohamedamine ftircharacterizationofsaharahoneyandpropolisandevaluationofitsanticandidalpotentials AT khiatibaghdad ftircharacterizationofsaharahoneyandpropolisandevaluationofitsanticandidalpotentials |
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1717766455268737024 |