Red blood cell distribution width in patients with limb, chest and head trauma
Introduction : This study investigated the values of red blood cell distribution width (RDW), an emerging and independent predictor of morbidity and mortality, in patients with limb, chest and head trauma. Material and methods : The study sample consisted of all patients who attended the emergency...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Termedia Publishing House
2017-04-01
|
Series: | Archives of Medical Science |
Subjects: | |
Online Access: | https://www.termedia.pl/Red-blood-cell-distribution-width-in-patients-with-limb-chest-and-head-trauma,19,29830,1,1.html |
id |
doaj-98c7c8ee839f41a8a14a0eec150a6c36 |
---|---|
record_format |
Article |
spelling |
doaj-98c7c8ee839f41a8a14a0eec150a6c362020-11-25T00:30:16ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512017-04-0113360661110.5114/aoms.2017.6728229830Red blood cell distribution width in patients with limb, chest and head traumaGiuseppe LippiChiara BovoRuggero BuonocoreMichele MitaritonnoGianfranco CervellinIntroduction : This study investigated the values of red blood cell distribution width (RDW), an emerging and independent predictor of morbidity and mortality, in patients with limb, chest and head trauma. Material and methods : The study sample consisted of all patients who attended the emergency department (ED) of the University Hospital of Parma for limb, chest and head traumas requiring admission to hospital wards during the year 2014. The controls consisted of outpatients living in the same geographical area and undergoing routine laboratory testing for health check-up. Results : The final study sample consisted of 290 patients with limb (n = 97), chest (n = 49) or head (n = 144) trauma and 967 outpatients. Significantly increased RDW values at admission were observed in all trauma patients compared with controls. Although the frequency of increased RDW (> 14.6%) was higher in all trauma patients than in controls, a subanalysis revealed that increased RDW values were significantly more frequent in patients with head trauma than in controls, but not in those with limb or chest trauma. In multivariate analysis, a significant association was found between head trauma and hemoglobin (p < 0.001) or RDW (p = 0.005). Head trauma patients had a ~3-fold higher likelihood of increased RDW values than controls. The negative and positive predictive values of increased RDW for predicting the presence of head trauma were 0.90 (95% CI: 0.88–0.92) and 0.24 (95% CI: 0.19–0.30). Conclusions : The results of this study highlight that RDW is increased in patients admitted to the ED with head trauma.https://www.termedia.pl/Red-blood-cell-distribution-width-in-patients-with-limb-chest-and-head-trauma,19,29830,1,1.htmltrauma injury anisocytosis red blood cell distribution width |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Giuseppe Lippi Chiara Bovo Ruggero Buonocore Michele Mitaritonno Gianfranco Cervellin |
spellingShingle |
Giuseppe Lippi Chiara Bovo Ruggero Buonocore Michele Mitaritonno Gianfranco Cervellin Red blood cell distribution width in patients with limb, chest and head trauma Archives of Medical Science trauma injury anisocytosis red blood cell distribution width |
author_facet |
Giuseppe Lippi Chiara Bovo Ruggero Buonocore Michele Mitaritonno Gianfranco Cervellin |
author_sort |
Giuseppe Lippi |
title |
Red blood cell distribution width in patients with limb, chest and head trauma |
title_short |
Red blood cell distribution width in patients with limb, chest and head trauma |
title_full |
Red blood cell distribution width in patients with limb, chest and head trauma |
title_fullStr |
Red blood cell distribution width in patients with limb, chest and head trauma |
title_full_unstemmed |
Red blood cell distribution width in patients with limb, chest and head trauma |
title_sort |
red blood cell distribution width in patients with limb, chest and head trauma |
publisher |
Termedia Publishing House |
series |
Archives of Medical Science |
issn |
1734-1922 1896-9151 |
publishDate |
2017-04-01 |
description |
Introduction : This study investigated the values of red blood cell distribution width (RDW), an emerging and independent predictor of morbidity and mortality, in patients with limb, chest and head trauma.
Material and methods : The study sample consisted of all patients who attended the emergency department (ED) of the University Hospital of Parma for limb, chest and head traumas requiring admission to hospital wards during the year 2014. The controls consisted of outpatients living in the same geographical area and undergoing routine laboratory testing for health check-up.
Results : The final study sample consisted of 290 patients with limb (n = 97), chest (n = 49) or head (n = 144) trauma and 967 outpatients. Significantly increased RDW values at admission were observed in all trauma patients compared with controls. Although the frequency of increased RDW (> 14.6%) was higher in all trauma patients than in controls, a subanalysis revealed that increased RDW values were significantly more frequent in patients with head trauma than in controls, but not in those with limb or chest trauma. In multivariate analysis, a significant association was found between head trauma and hemoglobin (p < 0.001) or RDW (p = 0.005). Head trauma patients had a ~3-fold higher likelihood of increased RDW values than controls. The negative and positive predictive values of increased RDW for predicting the presence of head trauma were 0.90 (95% CI: 0.88–0.92) and 0.24 (95% CI: 0.19–0.30).
Conclusions : The results of this study highlight that RDW is increased in patients admitted to the ED with head trauma. |
topic |
trauma injury anisocytosis red blood cell distribution width |
url |
https://www.termedia.pl/Red-blood-cell-distribution-width-in-patients-with-limb-chest-and-head-trauma,19,29830,1,1.html |
work_keys_str_mv |
AT giuseppelippi redbloodcelldistributionwidthinpatientswithlimbchestandheadtrauma AT chiarabovo redbloodcelldistributionwidthinpatientswithlimbchestandheadtrauma AT ruggerobuonocore redbloodcelldistributionwidthinpatientswithlimbchestandheadtrauma AT michelemitaritonno redbloodcelldistributionwidthinpatientswithlimbchestandheadtrauma AT gianfrancocervellin redbloodcelldistributionwidthinpatientswithlimbchestandheadtrauma |
_version_ |
1725327749706416128 |