Modulation of VEGF-A Alternative Splicing as a Novel Treatment in Chronic Kidney Disease

Vascular endothelial growth factor A (VEGF-A) is a prominent pro-angiogenic and pro-permeability factor in the kidney. Alternative splicing of the terminal exon of VEGF-A through the use of an alternative 3′ splice site gives rise to a functionally different family of isoforms, termed VEGF-Axxxb, kn...

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Bibliographic Details
Main Authors: Megan Stevens, Sebastian Oltean
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/9/2/98

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