Modulation of VEGF-A Alternative Splicing as a Novel Treatment in Chronic Kidney Disease
Vascular endothelial growth factor A (VEGF-A) is a prominent pro-angiogenic and pro-permeability factor in the kidney. Alternative splicing of the terminal exon of VEGF-A through the use of an alternative 3′ splice site gives rise to a functionally different family of isoforms, termed VEGF-Axxxb, kn...
Main Authors: | Megan Stevens, Sebastian Oltean |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-02-01
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Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/9/2/98 |
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