LncRNA-Gm9795 promotes inflammation in non-alcoholic steatohepatitis via NF- $$\kappa {}$$ κ B/JNK pathway by endoplasmic reticulum stress
Abstract Background Non-alcoholic steatohepatitis (NASH) is a key stage in leading development of non-alcoholic simple fatty liver (NAFL) into cirrhosis and even liver cancer. This study aimed at exploring the lncRNAs expression profile in NASH and the biological function of a novel LncRNA-gm9795. M...
Main Authors: | Liangying Ye, Dan Zhao, Yangzhi Xu, Jiaen Lin, Jiahui Xu, Kunyuan Wang, Zhanhui Ye, Yufeng Luo, Shiming Liu, Hui Yang |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
|
Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-021-02769-7 |
Similar Items
-
Epigenome-Wide Association Studies Provide Insight into the Pathogenesis of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis
by: Aybike Birerdinc, et al.
Published: (2018-01-01) -
Targeting of Secretory Proteins as a Therapeutic Strategy for Treatment of Nonalcoholic Steatohepatitis (NASH)
by: KyeongJin Kim, et al.
Published: (2020-03-01) -
Role of MicroRNAs in Pathophysiology of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis
by: Farzaneh Iravani, et al.
Published: (2018-10-01) -
Metabolomic Predictors of Non-alcoholic Steatohepatitis and Advanced Fibrosis in Children
by: Kattayoun Kordy, et al.
Published: (2021-08-01) -
Pathohistological characteristics of steatohepatitis on needle biopsy sample from 100 patients
by: Milićević Anđela, et al.
Published: (2019-01-01)