Endothelial function in normal and pathological conditions

• Main Authors: A. V. Pizov, N. A. Pizov, O. A. Skachkova, N. V. Pizovа
• Format: Article
• Language: Russian
• Published: Remedium Group LLC 2019-04-01
• Series: Медицинский совет
• Subjects: endothelial function; endothelial dysfunction; chronic diseases
• Online Access: https://www.med-sovet.pro/jour/article/view/2992

The article presents the data on the state of endothelial function in the normally and in various diseases and conditions. The basic  functions of endothelium in modulation of vascular tone, atrombogenicity and thrombogenicity of the vascular wall, regulation of  vascular wall adhesion, regulation of vascular growth are described. The main causes leading to the formation of endothelial  dysfunction and the mechanisms underlying it are highlighted. Numerous studies on the evaluation of endothelial function in  various diseases are presented. The basic methods of drug and non-drug correction of endothelial dysfunction are presented.