Hematobin is a novel immunomodulatory protein from the saliva of the horn fly Haematobia irritans that inhibits the inflammatory response in murine macrophages

Hematobin is a novel immunomodulatory protein from the saliva of the horn fly Haematobia irritans that inhibits the inflammatory response in murine macrophages

Abstract Background The horn fly Haematobia irritans is a blood-sucking ectoparasite responsible for substantial economic loss of livestock. Like other hematophagous arthropods species, the successful blood-feeding of H. irritans is highly dependent on the modulation of the host’s hemostasis and imm...

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Bibliographic Details
Main Authors: Martin Breijo, Eliane Esteves, Bruna Bizzarro, Priscila G. Lara, Josiane B. Assis, Sergio Rocha, Lucía Pastro, Cecilia Fernández, Ana Meikle, Anderson Sá-Nunes
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Parasites & Vectors
Subjects:
Haematobia irritans
Saliva
Hematobin
Macrophages
Inflammation
Immunomodulatory activity
Online Access:http://link.springer.com/article/10.1186/s13071-018-3017-z

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