CRISPR/Cas: a potential gene-editing tool in the nervous system

CRISPR/Cas: a potential gene-editing tool in the nervous system

Abstract The rapidly developmental RNA-guided CRISPR/Cas system is a powerful tool for RNA and DNA editing in a variety of cells from different species and makes a great contribution to gene function research, disease model generation and gene therapy development in the past few years. The ease of u...

Full description

Bibliographic Details
Main Authors: Yanxia Gao, Kexin Gao, Hui Yang
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:Cell Regeneration
Online Access:http://link.springer.com/article/10.1186/s13619-020-00044-6
id doaj-9904aab580ee4eb890244dafc66f9c35
record_format Article
spelling doaj-9904aab580ee4eb890244dafc66f9c352020-11-25T02:59:16ZengSpringerOpenCell Regeneration2045-97692020-08-01911810.1186/s13619-020-00044-6CRISPR/Cas: a potential gene-editing tool in the nervous systemYanxia Gao0Kexin Gao1Hui Yang2Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Chinese Academy of SciencesInstitute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Chinese Academy of SciencesInstitute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Chinese Academy of SciencesAbstract The rapidly developmental RNA-guided CRISPR/Cas system is a powerful tool for RNA and DNA editing in a variety of cells from different species and makes a great contribution to gene function research, disease model generation and gene therapy development in the past few years. The ease of use, low cost and high efficiency of CRISPR/Cas make it commonly used in various conditions. In this review, we introduce the CRISPR/Cas system and its diverse applications in nervous system briefly, which provides a better understanding for its potential application values.http://link.springer.com/article/10.1186/s13619-020-00044-6
collection DOAJ
language English
format Article
sources DOAJ
author Yanxia Gao
Kexin Gao
Hui Yang
spellingShingle Yanxia Gao
Kexin Gao
Hui Yang
CRISPR/Cas: a potential gene-editing tool in the nervous system
Cell Regeneration
author_facet Yanxia Gao
Kexin Gao
Hui Yang
author_sort Yanxia Gao
title CRISPR/Cas: a potential gene-editing tool in the nervous system
title_short CRISPR/Cas: a potential gene-editing tool in the nervous system
title_full CRISPR/Cas: a potential gene-editing tool in the nervous system
title_fullStr CRISPR/Cas: a potential gene-editing tool in the nervous system
title_full_unstemmed CRISPR/Cas: a potential gene-editing tool in the nervous system
title_sort crispr/cas: a potential gene-editing tool in the nervous system
publisher SpringerOpen
series Cell Regeneration
issn 2045-9769
publishDate 2020-08-01
description Abstract The rapidly developmental RNA-guided CRISPR/Cas system is a powerful tool for RNA and DNA editing in a variety of cells from different species and makes a great contribution to gene function research, disease model generation and gene therapy development in the past few years. The ease of use, low cost and high efficiency of CRISPR/Cas make it commonly used in various conditions. In this review, we introduce the CRISPR/Cas system and its diverse applications in nervous system briefly, which provides a better understanding for its potential application values.
url http://link.springer.com/article/10.1186/s13619-020-00044-6
work_keys_str_mv AT yanxiagao crisprcasapotentialgeneeditingtoolinthenervoussystem
AT kexingao crisprcasapotentialgeneeditingtoolinthenervoussystem
AT huiyang crisprcasapotentialgeneeditingtoolinthenervoussystem
_version_ 1724703367096172544

Similar Items