Paeonol Attenuated Inflammatory Response of Endothelial Cells via Stimulating Monocytes-Derived Exosomal MicroRNA-223

Paeonol Attenuated Inflammatory Response of Endothelial Cells via Stimulating Monocytes-Derived Exosomal MicroRNA-223

Introduction: Paeonol, an active compound isolated from the radix of Cortex Moutan, has been shown to have anti-atherosclerosis effects by regulating blood cells’ function and protecting vascular cells injury. Besides, emerging evidences has proven that exosomes might play a pivotal role in intercel...

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Bibliographic Details
Main Authors: Yarong Liu, Chao Li, Hongfei Wu, Xianmei Xie, Ying Sun, Min Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pharmacology
Subjects:
paeonol
atherosclerosis
lipopolysaccharide
exosomes
microRNA-223
STAT3
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01105/full

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