Managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizon
This review explores basic sleep physiology, the mechanism of action for each class of hypnotic agents, their clinical application based on pharmacodynamic and pharmacokinetic factors, and potential pharmacologic sleep-inducing mechanisms of future hypnotics. The paper challenges the reader to under...
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BioExcel Publishing Ltd
2013-10-01
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doaj-990beef9dcdf433392d1751c2ceaf8522020-11-24T23:29:02ZengBioExcel Publishing LtdDrugs in Context1740-43981740-43982013-10-0111010.7573/dic.212257Managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizonThomas L SchwartzViral GoradiaThis review explores basic sleep physiology, the mechanism of action for each class of hypnotic agents, their clinical application based on pharmacodynamic and pharmacokinetic factors, and potential pharmacologic sleep-inducing mechanisms of future hypnotics. The paper challenges the reader to understand the neuroscientific basis of insomnia and use this knowledge to guide prescription of hypnotic agents. Currently indicated hypnotic agents are discussed with regard to their mechanism of drug action and clinical application. A broader discussion is developed throughout this paper regarding other non-indicated agents that may improve sleep and describing newer pharmacological treatments that may become available in the future for use in sleep disorders and their comorbid conditions.http://www.drugsincontext.com/managing-insomnia-an-overview-of-insomnia-and-pharmacologic-treatment-strategies-in-use-and-on-the-horizon/hypnotic agentsinsomniasleepsedatives |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Thomas L Schwartz Viral Goradia |
spellingShingle |
Thomas L Schwartz Viral Goradia Managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizon Drugs in Context hypnotic agents insomnia sleep sedatives |
author_facet |
Thomas L Schwartz Viral Goradia |
author_sort |
Thomas L Schwartz |
title |
Managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizon |
title_short |
Managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizon |
title_full |
Managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizon |
title_fullStr |
Managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizon |
title_full_unstemmed |
Managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizon |
title_sort |
managing insomnia: an overview of insomnia and pharmacologic treatment strategies in use and on the horizon |
publisher |
BioExcel Publishing Ltd |
series |
Drugs in Context |
issn |
1740-4398 1740-4398 |
publishDate |
2013-10-01 |
description |
This review explores basic sleep physiology, the mechanism of action for each class of hypnotic agents, their clinical application based on pharmacodynamic and pharmacokinetic factors, and potential pharmacologic sleep-inducing mechanisms of future hypnotics. The paper challenges the reader to understand the neuroscientific basis of insomnia and use this knowledge to guide prescription of hypnotic agents. Currently indicated hypnotic agents are discussed with regard to their mechanism of drug action and clinical application. A broader discussion is developed throughout this paper regarding other non-indicated agents that may improve sleep and describing newer pharmacological treatments that may become available in the future for use in sleep disorders and their comorbid conditions. |
topic |
hypnotic agents insomnia sleep sedatives |
url |
http://www.drugsincontext.com/managing-insomnia-an-overview-of-insomnia-and-pharmacologic-treatment-strategies-in-use-and-on-the-horizon/ |
work_keys_str_mv |
AT thomaslschwartz managinginsomniaanoverviewofinsomniaandpharmacologictreatmentstrategiesinuseandonthehorizon AT viralgoradia managinginsomniaanoverviewofinsomniaandpharmacologictreatmentstrategiesinuseandonthehorizon |
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1725546897126457344 |