Fucoxanthin Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes

Fucoxanthin Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes

Fucoxanthin, a natural carotenoid, is abundant in seaweed with antioxidant properties. This study investigated the role of fucoxanthin in the induction of antioxidant enzymes involved in the synthesis of reduced glutathione (GSH), synthesized by glutamate-cysteine ligase catalytic subunit (GCLC) an...

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Bibliographic Details
Main Authors: Jian Zheng, Mei Jing Piao, Ki Cheon Kim, Cheng Wen Yao, Ji Won Cha, Jin Won Hyun
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Marine Drugs
Subjects:
fucoxanthin
NF-E2-related factor 2
oxidative stress
cytoprotection
PI3K/Akt
GCLC
GSS
GSH
Online Access:http://www.mdpi.com/1660-3397/12/7/4214

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