Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

Abstract Background Induction of strong T cell responses, in particular cytotoxic T cells, is a key for the generation of efficacious therapeutic cancer vaccines which yet, remains a major challenge for the vaccine developing world. Here we demonstrate that it is possible to harness the physiologica...

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Bibliographic Details
Main Authors: Mona O. Mohsen, Matthew D. Heath, Gustavo Cabral-Miranda, Cyrill Lipp, Andris Zeltins, Marcos Sande, Jens V. Stein, Carsten Riether, Elisa Roesti, Lisha Zha, Paul Engeroff, Aadil El-Turabi, Thomas M. Kundig, Monique Vogel, Murray A. Skinner, Daniel E. Speiser, Alexander Knuth, Matthias F. Kramer, Martin F. Bachmann
Format: Article
Language:English
Published: BMJ Publishing Group 2019-04-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Cucumber-mosaic virus CuMV
Virus-like particle VLP
Microcrystalline tyrosine MCT
Nano-vaccine
Online Access:http://link.springer.com/article/10.1186/s40425-019-0587-z

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