ANTIOXIDANT, ANTIBACTERIAL POTENTIAL AND HPLC ANALYSIS OF Dioscorea alata BULB

ANTIOXIDANT, ANTIBACTERIAL POTENTIAL AND HPLC ANALYSIS OF Dioscorea alata BULB

The purpose of the present study was to evaluate antioxidant, antibacterial potential and HPLC analysis of methanol extract of Dioscorea alata bulb. Antioxidant activity investigated by DPPH free radical scavenging assay, the IC50 value of plant extract was24.99µg/mL. Significant absorption of extra...

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Bibliographic Details
Main Authors: Md. Anisuzzman, Md. Nazmul Hasan Zilani, Sharmin Sultana Khushi, Md. Asaduzzman, Md. Golam Hossain
Format: Article
Language:English
Published: Universitas Gadjah Mada 2016-01-01
Series:Indonesian Journal of Pharmacy
Subjects:
Total Phenolic content
Myricetin
Scavenging activity
Disc diffusion
Online Access:http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1026
Description
Summary:The purpose of the present study was to evaluate antioxidant, antibacterial potential and HPLC analysis of methanol extract of Dioscorea alata bulb. Antioxidant activity investigated by DPPH free radical scavenging assay, the IC50 value of plant extract was24.99µg/mL. Significant absorption of extract (1.317 of 1mg/mL) showed the ferric reducing activity. HPLC analysis indicated the presence of myricetin (471.53mg/100 g of dry extract) in the highest concentration. Extract showed significant zone of inhibition in antibacterial activity test. The presence of myricetin along with other detected polyphenols might contribute to antioxidant and antibacterial activities.
ISSN:2338-9427
2338-9486

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