Failure of anti Interleukin-1 β monoclonal antibody in the treatment of recurrent pericarditis in two children

Failure of anti Interleukin-1 β monoclonal antibody in the treatment of recurrent pericarditis in two children

Abstract Background Recurrent pericarditis (RP) is a complication (15–30%) of acute pericarditis with an unknown etiology. Treatment regimen consists of a combination of non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine, with the addition of corticosteroids in resistant or intolerant cas...

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Bibliographic Details
Main Authors: Sara Signa, Matteo D’Alessandro, Rita Consolini, Angela Miniaci, Marta Bustaffa, Chiara Longo, Maria A. Tosca, Martina Bizzi, Roberta Caorsi, Leonardo Oliveira Mendonça, Andrea Pession, Angelo Ravelli, Marco Gattorno
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Recurrent pericarditis
Interleukin-1 β
Interleukin-1 α
Anakinra
Canakinumab
Online Access:http://link.springer.com/article/10.1186/s12969-020-00438-5

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