Mania associated with complicated hereditary spastic paraparesis
Hereditary spastic paraparesis (HSP) is an inherited group of neurological disorders with progressive lower limb spasticity. HSP can be clinically grouped into pure and complicated forms. Pure HSP is one without any associated neurological/psychiatric comorbidity. Depression is the most common psych...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2011-07-01
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doaj-992e27a0e2e248ac9e3a96b6b186d2652021-04-02T17:32:17ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neurosciences in Rural Practice0976-31470976-31552011-07-01020219019210.4103/0976-3147.83592Mania associated with complicated hereditary spastic paraparesisRaghavendra B Nayak0Govind S Bhogale1Nanasaheb M Patil2Aditya A PandurangiDepartment of Psychiatry, Jawaharlal Nehru Medical College, KLE University, Belgaum, Karnataka, IndiaDepartment of Psychiatry, Jawaharlal Nehru Medical College, KLE University, Belgaum, Karnataka, IndiaDepartment of Psychiatry, Jawaharlal Nehru Medical College, KLE University, Belgaum, Karnataka, IndiaHereditary spastic paraparesis (HSP) is an inherited group of neurological disorders with progressive lower limb spasticity. HSP can be clinically grouped into pure and complicated forms. Pure HSP is one without any associated neurological/psychiatric comorbidity. Depression is the most common psychiatric comorbidity. Presence of mania or bipolar affective illness with HSP is a rare phenomenon. We report a case of a 17-year-old boy who presented with classical features of HSP with complaints of excessive happiness, irritability, increased self-esteem and decreased sleep since 1 month. The patient also had complex partial seizure ever since he had features of HSP. The patient’s father and younger sister suffer from pure HSP. The patient was diagnosed to have first episode mania with complicated HSP. The details of treatment and possible neurobiology are discussed in this case report.http://www.thieme-connect.de/DOI/DOI?10.4103/0976-3147.83592complicated hereditary spastic paraparesishereditary spastic paraparesismania |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Raghavendra B Nayak Govind S Bhogale Nanasaheb M Patil Aditya A Pandurangi |
spellingShingle |
Raghavendra B Nayak Govind S Bhogale Nanasaheb M Patil Aditya A Pandurangi Mania associated with complicated hereditary spastic paraparesis Journal of Neurosciences in Rural Practice complicated hereditary spastic paraparesis hereditary spastic paraparesis mania |
author_facet |
Raghavendra B Nayak Govind S Bhogale Nanasaheb M Patil Aditya A Pandurangi |
author_sort |
Raghavendra B Nayak |
title |
Mania associated with complicated hereditary spastic paraparesis |
title_short |
Mania associated with complicated hereditary spastic paraparesis |
title_full |
Mania associated with complicated hereditary spastic paraparesis |
title_fullStr |
Mania associated with complicated hereditary spastic paraparesis |
title_full_unstemmed |
Mania associated with complicated hereditary spastic paraparesis |
title_sort |
mania associated with complicated hereditary spastic paraparesis |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
series |
Journal of Neurosciences in Rural Practice |
issn |
0976-3147 0976-3155 |
publishDate |
2011-07-01 |
description |
Hereditary spastic paraparesis (HSP) is an inherited group of neurological disorders with progressive lower limb spasticity. HSP can be clinically grouped into pure and complicated forms. Pure HSP is one without any associated neurological/psychiatric comorbidity. Depression is the most common psychiatric comorbidity. Presence of mania or bipolar affective illness with HSP is a rare phenomenon. We report a case of a 17-year-old boy who presented with classical features of HSP with complaints of excessive happiness, irritability, increased self-esteem and decreased sleep since 1 month. The patient also had complex partial seizure ever since he had features of HSP. The patient’s father and younger sister suffer from pure HSP. The patient was diagnosed to have first episode mania with complicated HSP. The details of treatment and possible neurobiology are discussed in this case report. |
topic |
complicated hereditary spastic paraparesis hereditary spastic paraparesis mania |
url |
http://www.thieme-connect.de/DOI/DOI?10.4103/0976-3147.83592 |
work_keys_str_mv |
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