Aspulvinones Suppress Postprandial Hyperglycemia as Potent α-Glucosidase Inhibitors From Aspergillus terreus ASM-1

Aspulvinones Suppress Postprandial Hyperglycemia as Potent α-Glucosidase Inhibitors From Aspergillus terreus ASM-1

Chemical investigation of Aspergillus terreus ASM-1 fermentation resulted in the isolation of three new prenylated aspulvinones V–X (1–3), together with the previously reported analogs, aspulvinone H (4), J-CR (5), and R (6). Their structures were elucidated by various spectroscopic methods includin...

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Bibliographic Details
Main Authors: Changjing Wu, Xiang Cui, Luzhen Sun, Jiajia Lu, Feng Li, Minghui Song, Yunxia Zhang, Xinqi Hao, Congkui Tian, Maoping Song, Xiaomeng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Chemistry
Subjects:
Aspergillus terreus
secondary metabolites
aspulvinone
structure elucidation
α-glucosidase inhibitory effect
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.736070/full

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