Theaflavins Improve Insulin Sensitivity through Regulating Mitochondrial Biosynthesis in Palmitic Acid-Induced HepG2 Cells

Theaflavins Improve Insulin Sensitivity through Regulating Mitochondrial Biosynthesis in Palmitic Acid-Induced HepG2 Cells

Theaflavins, the characteristic and bioactive polyphenols in black tea, possess the potential improving effects on insulin resistance-associated metabolic abnormalities, including obesity and type 2 diabetes mellitus. However, the related molecular mechanisms are still unclear. In this research, we...

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Bibliographic Details
Main Authors: Tuantuan Tong, Ning Ren, Park Soomi, Jiafan Wu, Na Guo, Hyunuk Kang, Eunhye Kim, Yuanyuan Wu, Puming He, Youying Tu, Bo Li
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
theaflavins
hepatocyte
insulin resistance
insulin signaling pathway
mitochondrial biogenesis
peroxisome proliferator-activated receptor coactivator-1 (PGC-1)
Online Access:https://www.mdpi.com/1420-3049/23/12/3382

Internet

https://www.mdpi.com/1420-3049/23/12/3382

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