Prognostic value of heart rhythm variability in patients with chronic heart failure (three-year investigation)

Aim: to estimate prognostic value of indicators of heart rhythm variability (HRV) in patients with chronic heart failure (CHF) within three years. Materials and methods: A total of 110 patients aged 55,2±6,5 years with CHF experienced Q-wave myocardial infarction were enrolled in the study. Analysis...

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Bibliographic Details
Main Author: Kosheleva N.A.
Format: Article
Language:Russian
Published: Saratov State Medical University 2011-12-01
Series:Саратовский научно-медицинский журнал
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Online Access:http://www.ssmj.ru/system/files/201104_845-850.pdf
Description
Summary:Aim: to estimate prognostic value of indicators of heart rhythm variability (HRV) in patients with chronic heart failure (CHF) within three years. Materials and methods: A total of 110 patients aged 55,2±6,5 years with CHF experienced Q-wave myocardial infarction were enrolled in the study. Analysis of HRV measures was obtained by means of 5 minutes records of standing at rest. Results: Within three years of supervision of patients 50 cases of cardiovascular complications were developed: 22 cases presented CHF regeneration, 13 patients suffered recurrent myocardial infarctions, lethal outcome was observed in 15 cases. It was established that at level of low-frequency spectrum HRV less than 5,2 In ms2 decompensations CHF (p=0,048) and lethal outcome (p=0,02) were determined than at bigger value of this indicator. Independent predictors of lethal outcome in patients with CHF within three years included the left ventricle ejection fraction, uric acid, N-terminal fragment of cerebral natriuretic peptide and low-frequency spectrum HRV. Conclusions: The developed algorithm of estimation of individual risk of lethal outcome development in CHF patients within three years, will allow to improve tactics and prognosis in this category of patients
ISSN:1995-0039
2076-2518