Runx3-mediated transcriptional program in cytotoxic lymphocytes.

The transcription factor Runx3 is highly expressed in CD8(+) T and NK cytotoxic lymphocytes and is required for their effective activation and proliferation but molecular insights into the transcription program regulated by Runx3 in these cells are still missing. Using Runx3-ChIP-seq and transcripto...

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Bibliographic Details
Main Authors: Joseph Lotem, Ditsa Levanon, Varda Negreanu, Dena Leshkowitz, Gilgi Friedlander, Yoram Groner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827420?pdf=render

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