Runx3-mediated transcriptional program in cytotoxic lymphocytes.
The transcription factor Runx3 is highly expressed in CD8(+) T and NK cytotoxic lymphocytes and is required for their effective activation and proliferation but molecular insights into the transcription program regulated by Runx3 in these cells are still missing. Using Runx3-ChIP-seq and transcripto...
Main Authors: | Joseph Lotem, Ditsa Levanon, Varda Negreanu, Dena Leshkowitz, Gilgi Friedlander, Yoram Groner |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3827420?pdf=render |
Similar Items
-
Runx3 prevents spontaneous colitis by directing the differentiation of anti-inflammatory mononuclear phagocytes.
by: Shay Hantisteanu, et al.
Published: (2020-01-01) -
Developmentally regulated promoter-switch transcriptionally controls <it>Runx1 </it>function during embryonic hematopoiesis
by: Goldenberg Dalia, et al.
Published: (2007-07-01) -
Transcriptional reprogramming of CD11b+Esam(hi) dendritic cell identity and function by loss of Runx3.
by: Joseph Dicken, et al.
Published: (2013-01-01) -
Addiction of t(8;21) and inv(16) Acute Myeloid Leukemia to Native RUNX1
by: Oren Ben-Ami, et al.
Published: (2013-09-01) -
The evolutionary origin of the Runx/CBFbeta transcription factors – Studies of the most basal metazoans
by: Groner Yoram, et al.
Published: (2008-08-01)