Strategies to Improve the Antitumor Effect of γδ T Cell Immunotherapy for Clinical Application

Strategies to Improve the Antitumor Effect of γδ T Cell Immunotherapy for Clinical Application

Human γδ T cells show potent cytotoxicity against various types of cancer cells in a major histocompatibility complex unrestricted manner. Phosphoantigens and nitrogen-containing bisphosphonates (N-bis) stimulate γδ T cells via interaction between the γδ T cell receptor (TCR) and butyrophilin subfam...

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Bibliographic Details
Main Authors:	Masatsugu Miyashita, Teruki Shimizu, Eishi Ashihara, Osamu Ukimura
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	International Journal of Molecular Sciences
Subjects:	γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor
Online Access:	https://www.mdpi.com/1422-0067/22/16/8910

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