Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea
Aims. Sleep disorders have recently become a significant public health problem worldwide and have deleterious health consequences. Obstructive sleep apnea (OSA) is the most common type of sleep-related breathing disorders. We aimed to evaluate anthropometric measurements, glucose metabolism, and cor...
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Series: | Pulmonary Medicine |
Online Access: | http://dx.doi.org/10.1155/2015/189761 |
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doaj-99b23e1fd639417dab5297ca22ef490e2020-11-24T23:06:43ZengHindawi LimitedPulmonary Medicine2090-18362090-18442015-01-01201510.1155/2015/189761189761Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep ApneaYaşar Yildirim0Süreyya Yilmaz1Mehmet Güven2Faruk Kılınç3Ali Veysel Kara4Zülfükar Yilmaz5Gökhan Kırbaş6Alpaslan Kemal Tuzcu7Fatma Yılmaz Aydın8Department of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, TurkeyDepartment of Pulmonology, Faculty of Medicine, Dicle University, Diyarbakır, TurkeyDepartment of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, TurkeyDepartment of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, TurkeyDepartment of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, TurkeyDepartment of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, TurkeyDepartment of Pulmonology, Faculty of Medicine, Dicle University, Diyarbakır, TurkeyDepartment of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, TurkeyDepartment of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, TurkeyAims. Sleep disorders have recently become a significant public health problem worldwide and have deleterious health consequences. Obstructive sleep apnea (OSA) is the most common type of sleep-related breathing disorders. We aimed to evaluate anthropometric measurements, glucose metabolism, and cortisol levels in patients with obstructive sleep apnea (OSA). Materials and Methods. A total of 50 patients with a body mass index ≥30 and major OSA symptoms were included in this study. Anthropometric measurements of the patients were recorded and blood samples were drawn for laboratory analysis. A 24-hour urine sample was also collected from each subject for measurement of 24-hour cortisol excretion. Patients were divided equally into 2 groups according to polysomnography results: control group with an apnea-hypopnea index (AHI) <5 (n=25) and OSA group with an AHI ≥5 (n=25). Results. Neck and waist circumference, fasting plasma glucose, HbA1c, late-night serum cortisol, morning serum cortisol after 1 mg dexamethasone suppression test, and 24-hour urinary cortisol levels were significantly higher in OSA patients compared to control subjects. Newly diagnosed DM was more frequent in patients with OSA than control subjects (32% versus 8%, p=0.034). There was a significant positive correlation between AHI and neck circumference, glucose, and late-night serum cortisol. Conclusions. Our study indicates that increased waist and neck circumferences constitute a risk for OSA regardless of obesity status. In addition, OSA has adverse effects on endocrine function and glucose metabolism.http://dx.doi.org/10.1155/2015/189761 |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yaşar Yildirim Süreyya Yilmaz Mehmet Güven Faruk Kılınç Ali Veysel Kara Zülfükar Yilmaz Gökhan Kırbaş Alpaslan Kemal Tuzcu Fatma Yılmaz Aydın |
spellingShingle |
Yaşar Yildirim Süreyya Yilmaz Mehmet Güven Faruk Kılınç Ali Veysel Kara Zülfükar Yilmaz Gökhan Kırbaş Alpaslan Kemal Tuzcu Fatma Yılmaz Aydın Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea Pulmonary Medicine |
author_facet |
Yaşar Yildirim Süreyya Yilmaz Mehmet Güven Faruk Kılınç Ali Veysel Kara Zülfükar Yilmaz Gökhan Kırbaş Alpaslan Kemal Tuzcu Fatma Yılmaz Aydın |
author_sort |
Yaşar Yildirim |
title |
Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea |
title_short |
Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea |
title_full |
Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea |
title_fullStr |
Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea |
title_full_unstemmed |
Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea |
title_sort |
evaluation of anthropometric and metabolic parameters in obstructive sleep apnea |
publisher |
Hindawi Limited |
series |
Pulmonary Medicine |
issn |
2090-1836 2090-1844 |
publishDate |
2015-01-01 |
description |
Aims. Sleep disorders have recently become a significant public health problem worldwide and have deleterious health consequences. Obstructive sleep apnea (OSA) is the most common type of sleep-related breathing disorders. We aimed to evaluate anthropometric measurements, glucose metabolism, and cortisol levels in patients with obstructive sleep apnea (OSA). Materials and Methods. A total of 50 patients with a body mass index ≥30 and major OSA symptoms were included in this study. Anthropometric measurements of the patients were recorded and blood samples were drawn for laboratory analysis. A 24-hour urine sample was also collected from each subject for measurement of 24-hour cortisol excretion. Patients were divided equally into 2 groups according to polysomnography results: control group with an apnea-hypopnea index (AHI) <5 (n=25) and OSA group with an AHI ≥5 (n=25). Results. Neck and waist circumference, fasting plasma glucose, HbA1c, late-night serum cortisol, morning serum cortisol after 1 mg dexamethasone suppression test, and 24-hour urinary cortisol levels were significantly higher in OSA patients compared to control subjects. Newly diagnosed DM was more frequent in patients with OSA than control subjects (32% versus 8%, p=0.034). There was a significant positive correlation between AHI and neck circumference, glucose, and late-night serum cortisol. Conclusions. Our study indicates that increased waist and neck circumferences constitute a risk for OSA regardless of obesity status. In addition, OSA has adverse effects on endocrine function and glucose metabolism. |
url |
http://dx.doi.org/10.1155/2015/189761 |
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