Investigation of the Healing Effects of Afyonkarahisar Region Hot Spring Waters' Inhalation on Experimentally Induced Asthma in Mice
Asthma is a chronic inflammatory disease of the airways observed exclusively in humans and sometimes animals. In this study, 40 Albino rats of the same age were used. After 6 weeks of ovalbumin-induced asthma in all animals, 40 rats were randomly divided into two groups as control and study groups f...
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Romanian Association of Balneology, Editura Balneara
2020-09-01
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doaj-99b25e34d78146229af2183ce143d4f02020-11-25T03:22:02ZengRomanian Association of Balneology, Editura BalnearaBalneo Research Journal2069-75972069-76192020-09-0111326126810.12680/balneo.2020.350Investigation of the Healing Effects of Afyonkarahisar Region Hot Spring Waters' Inhalation on Experimentally Induced Asthma in MiceELITOK Bülent0ULUSOY Yavuz1KİLİC Bahadir21. Afyon Kocatepe University, Faculty of Veterinary Medicine,2. Ministry of Agriculture and Forestry, Veterinary Control Central Research Institute, Pathology Laboratory, Ankara/ Turkey 2. Ministry of Agriculture and Forestry, Veterinary Control Central Research Institute, Pathology Laboratory, Ankara/ Turkey Asthma is a chronic inflammatory disease of the airways observed exclusively in humans and sometimes animals. In this study, 40 Albino rats of the same age were used. After 6 weeks of ovalbumin-induced asthma in all animals, 40 rats were randomly divided into two groups as control and study groups for a 21-day treatment period. At the treatment stage, the control group animals were treated with normal tap water, while the study group animals were treated with hot spring water. Clinical, hematological, blood biochemical and histopathological examinations were performed before starting the study, after asthma formation, and on days of 1st, 7th, 14th and 21st after treatment. Total leukocyte, neutrophil, monocyte, AST, ALT, GGT, total cholesterol, triglyceride levels were significantly decreased (p <0.05) in the study group animals which treated with hot spring water. These normalization changes were confirmed by histopathological findings. Consequently, it was concluded that hot spring water of Afyonkarahisar Region provide a very successful treatment in asthma, and it should be considered as a supportive option for the treatment of asthma.http://bioclima.ro/Balneo350.pdfasthmabalneotherapybiochemistryhematologyhistopathology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
ELITOK Bülent ULUSOY Yavuz KİLİC Bahadir |
spellingShingle |
ELITOK Bülent ULUSOY Yavuz KİLİC Bahadir Investigation of the Healing Effects of Afyonkarahisar Region Hot Spring Waters' Inhalation on Experimentally Induced Asthma in Mice Balneo Research Journal asthma balneotherapy biochemistry hematology histopathology |
author_facet |
ELITOK Bülent ULUSOY Yavuz KİLİC Bahadir |
author_sort |
ELITOK Bülent |
title |
Investigation of the Healing Effects of Afyonkarahisar Region Hot Spring Waters' Inhalation on Experimentally Induced Asthma in Mice |
title_short |
Investigation of the Healing Effects of Afyonkarahisar Region Hot Spring Waters' Inhalation on Experimentally Induced Asthma in Mice |
title_full |
Investigation of the Healing Effects of Afyonkarahisar Region Hot Spring Waters' Inhalation on Experimentally Induced Asthma in Mice |
title_fullStr |
Investigation of the Healing Effects of Afyonkarahisar Region Hot Spring Waters' Inhalation on Experimentally Induced Asthma in Mice |
title_full_unstemmed |
Investigation of the Healing Effects of Afyonkarahisar Region Hot Spring Waters' Inhalation on Experimentally Induced Asthma in Mice |
title_sort |
investigation of the healing effects of afyonkarahisar region hot spring waters' inhalation on experimentally induced asthma in mice |
publisher |
Romanian Association of Balneology, Editura Balneara |
series |
Balneo Research Journal |
issn |
2069-7597 2069-7619 |
publishDate |
2020-09-01 |
description |
Asthma is a chronic inflammatory disease of the airways observed exclusively in humans and sometimes animals. In this study, 40 Albino rats of the same age were used. After 6 weeks of ovalbumin-induced asthma in all animals, 40 rats were randomly divided into two groups as control and study groups for a 21-day treatment period. At the treatment stage, the control group animals were treated with normal tap water, while the study group animals were treated with hot spring water. Clinical, hematological, blood biochemical and histopathological examinations were performed before starting the study, after asthma formation, and on days of 1st, 7th, 14th and 21st after treatment. Total leukocyte, neutrophil, monocyte, AST, ALT, GGT, total cholesterol, triglyceride levels were significantly decreased (p <0.05) in the study group animals which treated with hot spring water. These normalization changes were confirmed by histopathological findings. Consequently, it was concluded that hot spring water of Afyonkarahisar Region provide a very successful treatment in asthma, and it should be considered as a supportive option for the treatment of asthma. |
topic |
asthma balneotherapy biochemistry hematology histopathology |
url |
http://bioclima.ro/Balneo350.pdf |
work_keys_str_mv |
AT elitokbulent investigationofthehealingeffectsofafyonkarahisarregionhotspringwatersinhalationonexperimentallyinducedasthmainmice AT ulusoyyavuz investigationofthehealingeffectsofafyonkarahisarregionhotspringwatersinhalationonexperimentallyinducedasthmainmice AT kilicbahadir investigationofthehealingeffectsofafyonkarahisarregionhotspringwatersinhalationonexperimentallyinducedasthmainmice |
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