Hydrodynamic Separation of Macromolecules, Particles and Cells
Separation of big chemical species, like proteins, DNA, polysaccarides, biological cells,is ubiquitous in industrial applications and fundamental research. Progress in biotech-nology and biomedical engineering need to make appeal to separation sciences fordeveloping new products. Although big progre...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universidad Nacional de Colombia
2003-01-01
|
| Series: | Acta Biológica Colombiana |
| Subjects: | |
| Online Access: | https://revistas.unal.edu.co/index.php/actabiol/article/view/26108 |
| Summary: | Separation of big chemical species, like proteins, DNA, polysaccarides, biological cells,is ubiquitous in industrial applications and fundamental research. Progress in biotech-nology and biomedical engineering need to make appeal to separation sciences fordeveloping new products. Although big progress have been made by the chromatographyand its related techniques concerning the separation of small and intermediate mol-ecules, those techniques are nevertheless inadequate for fraction-ating and analyzing bigspecies. In this paper we present the main phenomena implied in the separation processof macromolecules, particles and biological cells. Those phenomena have to be investi-gated by means of the fluid mechanics, the physical-chemistry end the analytical chem-istry. We emphasize on separation of species biggerthan one micrometer, by considering two not still very well known techniques, but with high developing potential: theField_Flow Fractionation, FFF, end the Split-flow Thin cell fractionation, SPLITT. |
|---|---|
| ISSN: | 0120-548X 1900-1649 |