Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness.

Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness.

Central corneal thickness (CCT), one of the most highly heritable human traits (h(2) typically>0.9), is important for the diagnosis of glaucoma and a potential risk factor for glaucoma susceptibility. We conducted genome-wide association studies in five cohorts from Australia and the United Kingd...

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Bibliographic Details
Main Authors: Yi Lu, David P Dimasi, Pirro G Hysi, Alex W Hewitt, Kathryn P Burdon, Tze'Yo Toh, Jonathan B Ruddle, Yi Ju Li, Paul Mitchell, Paul R Healey, Grant W Montgomery, Narelle Hansell, Timothy D Spector, Nicholas G Martin, Terri L Young, Christopher J Hammond, Stuart Macgregor, Jamie E Craig, David A Mackey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2869325?pdf=render

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http://europepmc.org/articles/PMC2869325?pdf=render

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