The Genotoxic and Pro-Apoptotic Activities of Advanced Glycation End-Products (MAGE) Measured with Micronuclei Assay Are Inhibited by Their Low Molecular Mass Counterparts

The Genotoxic and Pro-Apoptotic Activities of Advanced Glycation End-Products (MAGE) Measured with Micronuclei Assay Are Inhibited by Their Low Molecular Mass Counterparts

An association between the cancer invasive activities of cells and their exposure to advanced glycation end-products (AGEs) was described early in some reports. An incubation of cells with BSA–AGE (bovine serum albumin–AGE), BSA–carboxymethyllysine and BSA–methylglyoxal (BSA–MG) resulted in a signif...

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Bibliographic Details
Main Authors: Monika Czech, Maria Konopacka, Jacek Rogoliński, Zbigniew Maniakowski, Magdalena Staniszewska, Łukasz Łaczmański, Danuta Witkowska, Andrzej Gamian
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Genes
Subjects:
advanced glycation
glycation products
advanced glycation end-products
MAGEs
genotoxicity
apoptosis
Online Access:https://www.mdpi.com/2073-4425/12/5/729

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