Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria

Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria

Abstract Background In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure recommend fixed target doses of 0.25 or 0.5 mg/kg/day of primaquine for 14 days in glucose-6-phosphate dehydrogenase normal pati...

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Main Authors: Walter Robert Taylor, Richard M. Hoglund, Pimnara Peerawaranun, Thuy Nhien Nguyen, Tran Tinh Hien, Arnaud Tarantola, Lorenz von Seidlein, Rupam Tripura, Thomas J. Peto, Arjen M. Dondorp, Jordi Landier, Francois H.Nosten, Frank Smithuis, Koukeo Phommasone, Mayfong Mayxay, Soy Ty Kheang, Chy Say, Kak Neeraj, Leang Rithea, Lek Dysoley, Sim Kheng, Sinoun Muth, Arantxa Roca-Feltrer, Mark Debackere, Rick M. Fairhurst, Ngak Song, Philippe Buchy, Didier Menard, Nicholas J. White, Joel Tarning, Mavuto Mukaka
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Malaria Journal
Subjects:
Primaquine
Allometric scaling
Age-based dosing
Weight-based dosing
Plasmodium vivax
Online Access:https://doi.org/10.1186/s12936-021-03886-w

Internet

https://doi.org/10.1186/s12936-021-03886-w

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