NOA36 protein contains a highly conserved nucleolar localization signal capable of directing functional proteins to the nucleolus, in mammalian cells.

NOA36/ZNF330 is an evolutionarily well-preserved protein present in the nucleolus and mitochondria of mammalian cells. We have previously reported that the pro-apoptotic activity of this protein is mediated by a characteristic cysteine-rich domain. We now demonstrate that the nucleolar localization...

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Bibliographic Details
Main Authors: Ivan S de Melo, Maria D Jimenez-Nuñez, Concepción Iglesias, Antonio Campos-Caro, David Moreno-Sanchez, Felix A Ruiz, Jorge Bolívar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3596294?pdf=render