Wnt5a exhibits layer-specific expression in adult skin, is upregulated in psoriasis, and synergizes with type 1 interferon.

Wnt5a exhibits layer-specific expression in adult skin, is upregulated in psoriasis, and synergizes with type 1 interferon.

Wnt5a is a member of the wingless-type patterning regulators important in pre-natal development. The expression and distribution of Wnt5a and its receptors frizzled (fzd) 3 and fzd 5 in adult human skin have not been comprehensively studied to date.We here show that Wnt5a, fzd3, fzd5, as well as fzd...

Full description

Bibliographic Details
Main Authors: Malgorzata Romanowska, Alan Evans, David Kellock, Susan E Bray, Kathleen McLean, Susanne Donandt, John Foerster
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2670517?pdf=render

Similar Items

Similar Items