Emerging Roles of Cellular Metabolism in Regulating Dendritic Cell Subsets and Function

Emerging Roles of Cellular Metabolism in Regulating Dendritic Cell Subsets and Function

Dendritic cells (DCs) are the bridge between innate and T cell-dependent adaptive immunity and are promising therapeutic targets for cancer and immune-mediated disorders. Upon stimulation by pathogen or danger-sensing receptors, DCs become activated and poised to induce T cell priming. Recent studie...

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Bibliographic Details
Main Authors: Xingrong Du, Nicole M. Chapman, Hongbo Chi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
dendritic cell
metabolism
glycolysis
oxidative phosphorylation
fatty acid
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00152/full

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