How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist
Abstract Studies conducted in primary care as well as in psychiatric settings show that more than half of patients suffering from major depressive disorder (MDD) have poor adherence to antidepressants. Patients prematurely discontinue antidepressant therapy for various reasons, including patient-rel...
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doaj-9a1456212e9049e889b5c1355ea67bab2020-11-25T03:07:59ZengBMCAnnals of General Psychiatry1744-859X2020-10-011911810.1186/s12991-020-00306-2How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklistBernardo Dell’Osso0Umberto Albert1Giuseppe Carrà2Maurizio Pompili3Maria Giulia Nanni4Massimo Pasquini5Nicola Poloni6Andrea Raballo7Fabio Sambataro8Gianluca Serafini9Caterina Viganò10Koen Demyttenaere11Roger S. McIntyre12Andrea Fiorillo13Department of Biomedical and Clinical Sciences “Luigi Sacco”, University of MilanDepartment of Medicine, Surgery and Health Sciences, University of TriesteDepartment of Medicine and Surgery, University of Milan BicoccaDept. of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant‘Andrea Hospital, Sapienza University of RomeInstitute of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of FerraraDepartment of Human Neurosciences-Faculty of Medicine and Dentistry-SAPIENZA University of RomeDepartment of Medicine and Surgery, Section of Psychiatry, University of InsubriaSection of Psychiatry, Clinical Psychology and Rehabilitation, Department of Medicine, University of PerugiaSection of Psychiatry, Department of Neuroscience, University of PadovaInstitute of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of FerraraDepartment of Biomedical and Clinical Sciences “Luigi Sacco”, University of MilanCenter for Public Health Psychiatry, KU LeuvenMood Disorders Psychopharmacology Unit, University Health NetworkDepartment of Psychiatry, University of Campania “L. Vanvitelli”Abstract Studies conducted in primary care as well as in psychiatric settings show that more than half of patients suffering from major depressive disorder (MDD) have poor adherence to antidepressants. Patients prematurely discontinue antidepressant therapy for various reasons, including patient-related (e.g., misperceptions about antidepressants, side-effects, and lack of tolerability), clinician-related (e.g., insufficient instruction received by clinicians about the medication, lack of shared decision-making, and follow-up care), as well as structural factors (e.g., access, cost, and stigma). The high rate of poor adherence to antidepressant treatments provides the impetus for identifying factors that are contributing to noncompliance in an individual patient, to implement a careful education about this phenomenon. As adherence to antidepressants is one of the major unmet needs in MDD treatment, being associated with negative outcomes, we sought to identify a series of priorities to be discussed with persons with MDD with the larger aim to improve treatment adherence. To do so, we analyzed a series of epidemiological findings and clinical reasons for this phenomenon, and then proceeded to define through a multi-step consensus a set of recommendations to be provided by psychiatrists and other practitioners at the time of the first (prescription) visit with patients. Herein, we report the results of this initiative.http://link.springer.com/article/10.1186/s12991-020-00306-2AdherenceAntidepressantsMajor depressive disorderConsensusConcordance |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bernardo Dell’Osso Umberto Albert Giuseppe Carrà Maurizio Pompili Maria Giulia Nanni Massimo Pasquini Nicola Poloni Andrea Raballo Fabio Sambataro Gianluca Serafini Caterina Viganò Koen Demyttenaere Roger S. McIntyre Andrea Fiorillo |
spellingShingle |
Bernardo Dell’Osso Umberto Albert Giuseppe Carrà Maurizio Pompili Maria Giulia Nanni Massimo Pasquini Nicola Poloni Andrea Raballo Fabio Sambataro Gianluca Serafini Caterina Viganò Koen Demyttenaere Roger S. McIntyre Andrea Fiorillo How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist Annals of General Psychiatry Adherence Antidepressants Major depressive disorder Consensus Concordance |
author_facet |
Bernardo Dell’Osso Umberto Albert Giuseppe Carrà Maurizio Pompili Maria Giulia Nanni Massimo Pasquini Nicola Poloni Andrea Raballo Fabio Sambataro Gianluca Serafini Caterina Viganò Koen Demyttenaere Roger S. McIntyre Andrea Fiorillo |
author_sort |
Bernardo Dell’Osso |
title |
How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist |
title_short |
How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist |
title_full |
How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist |
title_fullStr |
How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist |
title_full_unstemmed |
How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist |
title_sort |
how to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist |
publisher |
BMC |
series |
Annals of General Psychiatry |
issn |
1744-859X |
publishDate |
2020-10-01 |
description |
Abstract Studies conducted in primary care as well as in psychiatric settings show that more than half of patients suffering from major depressive disorder (MDD) have poor adherence to antidepressants. Patients prematurely discontinue antidepressant therapy for various reasons, including patient-related (e.g., misperceptions about antidepressants, side-effects, and lack of tolerability), clinician-related (e.g., insufficient instruction received by clinicians about the medication, lack of shared decision-making, and follow-up care), as well as structural factors (e.g., access, cost, and stigma). The high rate of poor adherence to antidepressant treatments provides the impetus for identifying factors that are contributing to noncompliance in an individual patient, to implement a careful education about this phenomenon. As adherence to antidepressants is one of the major unmet needs in MDD treatment, being associated with negative outcomes, we sought to identify a series of priorities to be discussed with persons with MDD with the larger aim to improve treatment adherence. To do so, we analyzed a series of epidemiological findings and clinical reasons for this phenomenon, and then proceeded to define through a multi-step consensus a set of recommendations to be provided by psychiatrists and other practitioners at the time of the first (prescription) visit with patients. Herein, we report the results of this initiative. |
topic |
Adherence Antidepressants Major depressive disorder Consensus Concordance |
url |
http://link.springer.com/article/10.1186/s12991-020-00306-2 |
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