Synthesis of Biotin-Tagged Chitosan Oligosaccharides and Assessment of Their Immunomodulatory Activity

Synthesis of Biotin-Tagged Chitosan Oligosaccharides and Assessment of Their Immunomodulatory Activity

Chitin, a polymer of β-(1→4)-linked N-acetyl-d-glucosamine, is one of the main polysaccharide components of the fungal cell wall. Its N-deacetylated form, chitosan, is enzymatically produced in the cell wall by chitin deacetylases. It exerts immunomodulative, anti-inflammatory, anti-cancer, anti-bac...

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Bibliographic Details
Main Authors:	Yury E. Tsvetkov, Ema Paulovičová, Lucia Paulovičová, Pavol Farkaš, Nikolay E. Nifantiev
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-12-01
Series:	Frontiers in Chemistry
Subjects:	chitin chitosan chitosan oligosaccharides synthesis glycosylation aglycon transfer
Online Access:	https://www.frontiersin.org/articles/10.3389/fchem.2020.554732/full

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