Biomarker Evaluation and Toxic Effects of an Acute Oral and Systemic Fumonisin Exposure of Pigs with a Special Focus on Dietary Fumonisin Esterase Supplementation

Biomarker Evaluation and Toxic Effects of an Acute Oral and Systemic Fumonisin Exposure of Pigs with a Special Focus on Dietary Fumonisin Esterase Supplementation

The mycotoxin fumonisin B1 (FB1) is a frequent contaminant of feed. It causes a disruption of sphingolipid metabolism and pulmonary, hepatic, and immunological lesions in pigs depending on the exposure scenario. One sensitive biomarker for FB1 exposure is the sphinganine (Sa) to sphingosine (So) rat...

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Bibliographic Details
Main Authors: Hanna Schertz, Sven Dänicke, Jana Frahm, Dian Schatzmayr, Ilse Dohnal, Gerlinde Bichl, Heidi E. Schwartz-Zimmermann, Sonia Colicchia, Gerhard Breves, Jens P. Teifke, Jeannette Kluess
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Toxins
Subjects:
fumonisin
pigs
Sa/So ratio
single-dose
clinical examination
blood count
clinical biochemistry
fumonisin esterase
Online Access:http://www.mdpi.com/2072-6651/10/7/296

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