Correction of Heritable Epigenetic Defects Using Editing Tools
Epimutations refer to mistakes in the setting or maintenance of epigenetic marks in the chromatin. They lead to mis-expression of genes and are often secondary to germline transmitted mutations. As such, they are the cause for a considerable number of genetically inherited conditions in humans. The...
Main Authors: | Tayma Handal, Rachel Eiges |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/8/3966 |
Similar Items
-
Epigenome engineering in cancer: fairytale or a realistic path to the clinic?
by: Fahimeh eFalahi, et al.
Published: (2015-02-01) -
Epigenetic modulators of monocytic function: implication for steady state and disease in the CNS .
by: F. Nina Papavasiliou, et al.
Published: (2016-01-01) -
AlphaBeta: computational inference of epimutation rates and spectra from high-throughput DNA methylation data in plants
by: Yadollah Shahryary, et al.
Published: (2020-10-01) -
Epigenetic Footprints of CRISPR/Cas9-Mediated Genome Editing in Plants
by: Jun Hyung Lee, et al.
Published: (2020-01-01) -
Gene-Specific Targeting of DNA Methylation in the Mammalian Genome
by: Arthur Urbano, et al.
Published: (2019-10-01)