A novel circular RNA hsa_circRNA_103809/miR-377-3p/GOT1 pathway regulates cisplatin-resistance in non-small cell lung cancer (NSCLC)

Abstract Background Cisplatin is the first-line chemotherapeutic drug for non-small cell lung cancer (NSCLC), and emerging evidences suggests that targeting circular RNAs (circRNAs) is an effective strategy to increase cisplatin-sensitivity in NSCLC, but the detailed mechanisms are still not fully d...

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Bibliographic Details
Main Authors: Xiang Zhu, Jing Han, Huiyin Lan, Qingren Lin, Yuezhen Wang, Xiaojiang Sun
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-020-07680-w