Retinoblastoma presenting as pseudohypopyon and preserved visual acuity
Purpose: To describe a Case of retinoblastoma that presented subtly as a pseudohypopyon in a child with preserved visual acuity. Observations: A 3-year-old male was referred for concern of hypopyon in the left eye. Initial examination revealed 20/30 vision, a pseudohypopyon, and a large white mass o...
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doaj-9a4547e643d84cedb580f9586a62095e2021-08-23T04:56:59ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362021-09-0123101141Retinoblastoma presenting as pseudohypopyon and preserved visual acuityAndrea L. Blitzer0Sidney A. Schechet1Hassan A. Shah2Michael P. Blair3Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, USAElman Retina Group, Baltimore, MD, USADepartment of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, USADepartment of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, USA; Retina Consultants, Ltd, Des Plaines, IL, USA; Corresponding author. Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, USA.Purpose: To describe a Case of retinoblastoma that presented subtly as a pseudohypopyon in a child with preserved visual acuity. Observations: A 3-year-old male was referred for concern of hypopyon in the left eye. Initial examination revealed 20/30 vision, a pseudohypopyon, and a large white mass on fundoscopy. Examination under anesthesia revealed extensive retinoblastoma with vitreous seeds and anterior chamber involvement. Enucleation was performed and histology demonstrated retinoblastoma with tumor cells found within the ciliary body, iris, iridocorneal angle, and Schlemm canal. Based on the high-risk histopathology findings, adjuvant chemotherapy was performed. Conclusions and importance: Retinoblastoma is the most common primary intraocular malignancy in children. Though the classic presentation is leukocoria and/or strabismus, it can present in a variety of ways. Physicians should be aware that retinoblastoma, even severe forms, can present subtly with pseudohypopyon and preserved vision. Adjuvant chemotherapy for anterior segment involvement remains controversial.http://www.sciencedirect.com/science/article/pii/S245199362100150XRetinoblastomaPseudohypopyonEnucleationHistopathologyAnterior segment tumor |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Andrea L. Blitzer Sidney A. Schechet Hassan A. Shah Michael P. Blair |
spellingShingle |
Andrea L. Blitzer Sidney A. Schechet Hassan A. Shah Michael P. Blair Retinoblastoma presenting as pseudohypopyon and preserved visual acuity American Journal of Ophthalmology Case Reports Retinoblastoma Pseudohypopyon Enucleation Histopathology Anterior segment tumor |
author_facet |
Andrea L. Blitzer Sidney A. Schechet Hassan A. Shah Michael P. Blair |
author_sort |
Andrea L. Blitzer |
title |
Retinoblastoma presenting as pseudohypopyon and preserved visual acuity |
title_short |
Retinoblastoma presenting as pseudohypopyon and preserved visual acuity |
title_full |
Retinoblastoma presenting as pseudohypopyon and preserved visual acuity |
title_fullStr |
Retinoblastoma presenting as pseudohypopyon and preserved visual acuity |
title_full_unstemmed |
Retinoblastoma presenting as pseudohypopyon and preserved visual acuity |
title_sort |
retinoblastoma presenting as pseudohypopyon and preserved visual acuity |
publisher |
Elsevier |
series |
American Journal of Ophthalmology Case Reports |
issn |
2451-9936 |
publishDate |
2021-09-01 |
description |
Purpose: To describe a Case of retinoblastoma that presented subtly as a pseudohypopyon in a child with preserved visual acuity. Observations: A 3-year-old male was referred for concern of hypopyon in the left eye. Initial examination revealed 20/30 vision, a pseudohypopyon, and a large white mass on fundoscopy. Examination under anesthesia revealed extensive retinoblastoma with vitreous seeds and anterior chamber involvement. Enucleation was performed and histology demonstrated retinoblastoma with tumor cells found within the ciliary body, iris, iridocorneal angle, and Schlemm canal. Based on the high-risk histopathology findings, adjuvant chemotherapy was performed. Conclusions and importance: Retinoblastoma is the most common primary intraocular malignancy in children. Though the classic presentation is leukocoria and/or strabismus, it can present in a variety of ways. Physicians should be aware that retinoblastoma, even severe forms, can present subtly with pseudohypopyon and preserved vision. Adjuvant chemotherapy for anterior segment involvement remains controversial. |
topic |
Retinoblastoma Pseudohypopyon Enucleation Histopathology Anterior segment tumor |
url |
http://www.sciencedirect.com/science/article/pii/S245199362100150X |
work_keys_str_mv |
AT andrealblitzer retinoblastomapresentingaspseudohypopyonandpreservedvisualacuity AT sidneyaschechet retinoblastomapresentingaspseudohypopyonandpreservedvisualacuity AT hassanashah retinoblastomapresentingaspseudohypopyonandpreservedvisualacuity AT michaelpblair retinoblastomapresentingaspseudohypopyonandpreservedvisualacuity |
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