Denosumab Regulates Gut Microbiota Composition and Cytokines in Dinitrobenzene Sulfonic Acid (DNBS)-Experimental Colitis

Denosumab Regulates Gut Microbiota Composition and Cytokines in Dinitrobenzene Sulfonic Acid (DNBS)-Experimental Colitis

The pro-inflammatory mediator receptor activator of nuclear factor-kappa B ligand (RANKL) plays a significant role in the development of rheumatoid arthritis; however, its role in inflammatory bowel disease is unknown. Genome-wide association meta-analysis for Crohn’s disease (CD) identified a varia...

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Bibliographic Details
Main Authors: Azin Khafipour, Nour Eissa, Peris M. Munyaka, Mohammad F. Rabbi, Kunal Kapoor, Laetitia Kermarrec, Ehsan Khafipour, Charles N. Bernstein, Jean-Eric Ghia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
IBD
immunotherapy
immune responses
gut microbes
TNF
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01405/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01405/full

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