Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins

Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins

The human cytomegalovirus (HCMV)-encoded cyclin-dependent kinase (CDK) ortholog pUL97 associates with human cyclin B1 and other types of cyclins. Here, the question was addressed whether cyclin interaction of pUL97 and additional viral proteins is detectable by mass spectrometry-based approaches. Pr...

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Bibliographic Details
Main Authors: Mirjam Steingruber, Alexandra Kraut, Eileen Socher, Heinrich Sticht, Anna Reichel, Thomas Stamminger, Bushra Amin, Yohann Couté, Corina Hutterer, Manfred Marschall
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Viruses
Subjects:
human cytomegalovirus
CDK ortholog pUL97
human cyclins
cyclin-associated protein complexes
proteomic analysis
molecular modeling
Online Access:http://www.mdpi.com/1999-4915/8/8/219

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