Predicting adverse outcomes in obstetric sepsis using modified sepsis scores
Background: Obstetric sepsis continues to be one of the major causes of maternal mortality. Assessment of obstetric sepsis and management plans need to take into consideration the altered immunological and physiological responses of pregnancy. Obstetrically modified Sequential Organ Failure Assessme...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Barpeta Obstetrics and Gynaecological Society
2021-01-01
|
Series: | New Indian Journal of OBGYN |
Subjects: | |
Online Access: | https://journal.barpetaogs.co.in/pdf/07129.pdf |
id |
doaj-9a62bf4ccae741bc883c5cd20a6eca08 |
---|---|
record_format |
Article |
spelling |
doaj-9a62bf4ccae741bc883c5cd20a6eca082021-01-30T05:07:18ZengBarpeta Obstetrics and Gynaecological SocietyNew Indian Journal of OBGYN2454-23342454-23422021-01-017212913410.21276/obgyn.2021.7.2.4Predicting adverse outcomes in obstetric sepsis using modified sepsis scoresAmita Ray0Debjani Goswami1Bharath Kumar2Professor and HOD, Department of Obstetrics and Gynecology, IQ City Medical College Durgapur, West Bengal, IndiaAssistant Professor, Department of Medicine, IQ City Medical College Durgapur West Bengal, IndiaAssociate Statistician Biostatistics, Glaxo Smith-Kline Asia Pvt . Ltd. Bangalore, IndiaBackground: Obstetric sepsis continues to be one of the major causes of maternal mortality. Assessment of obstetric sepsis and management plans need to take into consideration the altered immunological and physiological responses of pregnancy. Obstetrically modified Sequential Organ Failure Assessment (omSOFA) and quick omSOFA (omqSOFA) scores have been proposed which take into account these altered responses. Objectives: We did this study with the objective of comparing the omSOFA and omqSOFA scores with the original SOFA and original quick SOFA (q-SOFA) scores to find which of these better predicted the outcomes of mortality, intensive care unit (ICU) stay and hospital stay in patients with obstetric sepsis. Materials and methods: All cases of obstetric sepsis admitted to our hospital ICU during the period August 2018 to July 2019 were included in this study. The SOFA scores, and the obstetrically modified SOFA scores were calculated, sepsis biomarkers send and all were assessed for their ability to predict mortality using binary logistic regression. Results: There was a significant association (p< 0.001) between mortality and the SOFA, om-SOFA and omq-SOFA scores. The q-SOFA score was not significantly associated with mortality (p value= 0.315). The om-SOFA proved to be the best predictor of mortality. Adding biomarkers to the calculations did not significantly improve the predictability of the om-SOFA score. Conclusion: Modifying the SOFA scores has increased the predictability of mortality in obstetric sepsis and these should be used when assessing and monitoring this special category of sepsis patients.https://journal.barpetaogs.co.in/pdf/07129.pdfsepsissequential organ failure assessment (sofa) |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Amita Ray Debjani Goswami Bharath Kumar |
spellingShingle |
Amita Ray Debjani Goswami Bharath Kumar Predicting adverse outcomes in obstetric sepsis using modified sepsis scores New Indian Journal of OBGYN sepsis sequential organ failure assessment (sofa) |
author_facet |
Amita Ray Debjani Goswami Bharath Kumar |
author_sort |
Amita Ray |
title |
Predicting adverse outcomes in obstetric sepsis using modified sepsis scores |
title_short |
Predicting adverse outcomes in obstetric sepsis using modified sepsis scores |
title_full |
Predicting adverse outcomes in obstetric sepsis using modified sepsis scores |
title_fullStr |
Predicting adverse outcomes in obstetric sepsis using modified sepsis scores |
title_full_unstemmed |
Predicting adverse outcomes in obstetric sepsis using modified sepsis scores |
title_sort |
predicting adverse outcomes in obstetric sepsis using modified sepsis scores |
publisher |
Barpeta Obstetrics and Gynaecological Society |
series |
New Indian Journal of OBGYN |
issn |
2454-2334 2454-2342 |
publishDate |
2021-01-01 |
description |
Background: Obstetric sepsis continues to be one of the major causes of maternal mortality. Assessment of obstetric sepsis and management plans need to take into consideration the altered immunological and physiological responses of pregnancy. Obstetrically modified Sequential Organ Failure Assessment (omSOFA) and quick omSOFA (omqSOFA) scores have been proposed which take into account these altered responses. Objectives: We did this study with the objective of comparing the omSOFA and omqSOFA scores with the original SOFA and original quick SOFA (q-SOFA) scores to find which of these better predicted the outcomes of mortality, intensive care unit (ICU) stay and hospital stay in patients with obstetric sepsis. Materials and methods: All cases of obstetric sepsis admitted to our hospital ICU during the period August 2018 to July 2019 were included in this study. The SOFA scores, and the obstetrically modified SOFA scores were calculated, sepsis biomarkers send and all were assessed for their ability to predict mortality using binary logistic regression. Results: There was a significant association (p< 0.001) between mortality and the SOFA, om-SOFA and omq-SOFA scores. The q-SOFA score was not significantly associated with mortality (p value= 0.315). The om-SOFA proved to be the best predictor of mortality. Adding biomarkers to the calculations did not significantly improve the predictability of the om-SOFA score. Conclusion: Modifying the SOFA scores has increased the predictability of mortality in obstetric sepsis and these should be used when assessing and monitoring this special category of sepsis patients. |
topic |
sepsis sequential organ failure assessment (sofa) |
url |
https://journal.barpetaogs.co.in/pdf/07129.pdf |
work_keys_str_mv |
AT amitaray predictingadverseoutcomesinobstetricsepsisusingmodifiedsepsisscores AT debjanigoswami predictingadverseoutcomesinobstetricsepsisusingmodifiedsepsisscores AT bharathkumar predictingadverseoutcomesinobstetricsepsisusingmodifiedsepsisscores |
_version_ |
1724318195953696768 |