Automated computational detection, quantitation, and mapping of mitosis in whole-slide images for clinically actionable surgical pathology decision support
Background: Determining mitotic index by counting mitotic figures (MFs) microscopically from tumor areas with most abundant MF (hotspots [HS]) produces a prognostically useful tumor grading biomarker. However, interobserver concordance identifying MF and HS can be poorly reproducible. Immunolabeling...
Main Authors: | Munish Puri, Shelley B Hoover, Stephen M Hewitt, Bih-Rong Wei, Hibret Amare Adissu, Charles H C Halsey, Jessica Beck, Charles Bradley, Sarah D Cramer, Amy C Durham, D Glen Esplin, Chad Frank, L Tiffany Lyle, Lawrence D McGill, Melissa D Sánchez, Paula A Schaffer, Ryan P Traslavina, Elizabeth Buza, Howard H Yang, Maxwell P Lee, Jennifer E Dwyer, R Mark Simpson |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2019-01-01
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Series: | Journal of Pathology Informatics |
Subjects: | |
Online Access: | http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2019;volume=10;issue=1;spage=4;epage=4;aulast=Puri |
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