Xanthoceraside induces cell apoptosis through downregulation of the PI3K/Akt/Bcl-2/Bax signaling pathway in cell lines of human bladder cancer

Xanthoceraside induces cell apoptosis through downregulation of the PI3K/Akt/Bcl-2/Bax signaling pathway in cell lines of human bladder cancer

Background: Xanthoceraside is a component obtained in the husks of Xanthoceras sorbifolia Bunge. Series of researches proved that xanthoceraside had functions of anti-inflammation and anti-tumor effects. However, the mechanisms of xanthoceraside against bladder cancer are unclear. Accordingly, we pr...

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Bibliographic Details
Main Authors: Xue Chai, Jian-Wu Zhang, Sheng-Hui Li, Qing-Shui Cheng, Ming-Ming Qin, Chun-Yan Yang, Jia-Lin Gao, Hou-Bao Huang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
apoptosis
bladder cancer
signaling pathway
xanthoceraside
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=2;spage=294;epage=301;aulast=Chai

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