Efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopy
Background Because of its efficacy and safety, polyethylene glycol (PEG) is generally used to prepare for colonoscopy. However, the side effects of PEG, including nausea, vomiting, abdominal discomfort, pain, and general weakness, tend to decrease patient compliance and satisfaction. The aim of this...
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Yeungnam University College of Medicine
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doaj-9a92ffd24b2c44258fd649be8252002a2020-11-25T01:05:14ZengYeungnam University College of MedicineYeungnam University Journal of Medicine2384-02932019-05-013629910410.12701/yujm.2019.000802397Efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopyMin Kyu Kang0Byung Ik JangJun Suk Park1Kyeong Ok Kim2 Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, KoreaBackground Because of its efficacy and safety, polyethylene glycol (PEG) is generally used to prepare for colonoscopy. However, the side effects of PEG, including nausea, vomiting, abdominal discomfort, pain, and general weakness, tend to decrease patient compliance and satisfaction. The aim of this study is to investigate the efficacy and safety of PEG with 0.1 mg ramosetron on colonoscopy patients who had difficulty taking PEG due to side effects or large volume. Methods From January to August in 2012, 28 patients who visited Yeungnam University hospital for a colonoscopy were prospectively enrolled. All enrolled patients were previous history underwent colonoscopy using PEG only in our hospital. The efficacy and safety of ramosetron were assessed through the use of a questionnaire, and compared previous bowel preparation. Results Compared to previous examination, the patients using the ramosetron reported less nausea, vomiting, abdominal discomfort, and abdominal pain, as well as a higher degree of compliance and satisfaction of the patient. There were no side effects reported with the use of ramosetron. However, overall bowel preparation quality was not better than the previous examination. Conclusion In case of the use of ramosetron in combination with PEG for bowel preparation, patients experienced a higher rate of compliance and tolerance. Looking forward, ramosetron may become an option of pretreatment for bowel preparation.http://yujm.yu.ac.kr/upload/pdf/yujm-2019-00080.pdfBowel preparationColonoscopyPolyethylene glycolRamosetron |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Min Kyu Kang Byung Ik Jang Jun Suk Park Kyeong Ok Kim |
spellingShingle |
Min Kyu Kang Byung Ik Jang Jun Suk Park Kyeong Ok Kim Efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopy Yeungnam University Journal of Medicine Bowel preparation Colonoscopy Polyethylene glycol Ramosetron |
author_facet |
Min Kyu Kang Byung Ik Jang Jun Suk Park Kyeong Ok Kim |
author_sort |
Min Kyu Kang |
title |
Efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopy |
title_short |
Efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopy |
title_full |
Efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopy |
title_fullStr |
Efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopy |
title_full_unstemmed |
Efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopy |
title_sort |
efficacy of ramosetron in combination with polyethylene glycol of preparing for a colonoscopy |
publisher |
Yeungnam University College of Medicine |
series |
Yeungnam University Journal of Medicine |
issn |
2384-0293 |
publishDate |
2019-05-01 |
description |
Background Because of its efficacy and safety, polyethylene glycol (PEG) is generally used to prepare for colonoscopy. However, the side effects of PEG, including nausea, vomiting, abdominal discomfort, pain, and general weakness, tend to decrease patient compliance and satisfaction. The aim of this study is to investigate the efficacy and safety of PEG with 0.1 mg ramosetron on colonoscopy patients who had difficulty taking PEG due to side effects or large volume. Methods From January to August in 2012, 28 patients who visited Yeungnam University hospital for a colonoscopy were prospectively enrolled. All enrolled patients were previous history underwent colonoscopy using PEG only in our hospital. The efficacy and safety of ramosetron were assessed through the use of a questionnaire, and compared previous bowel preparation. Results Compared to previous examination, the patients using the ramosetron reported less nausea, vomiting, abdominal discomfort, and abdominal pain, as well as a higher degree of compliance and satisfaction of the patient. There were no side effects reported with the use of ramosetron. However, overall bowel preparation quality was not better than the previous examination. Conclusion In case of the use of ramosetron in combination with PEG for bowel preparation, patients experienced a higher rate of compliance and tolerance. Looking forward, ramosetron may become an option of pretreatment for bowel preparation. |
topic |
Bowel preparation Colonoscopy Polyethylene glycol Ramosetron |
url |
http://yujm.yu.ac.kr/upload/pdf/yujm-2019-00080.pdf |
work_keys_str_mv |
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