Lack of Connexins 40 and 45 Reduces Local and Conducted Vasoconstrictor Responses in the Murine Afferent Arterioles

Lack of Connexins 40 and 45 Reduces Local and Conducted Vasoconstrictor Responses in the Murine Afferent Arterioles

The juxtaglomerular apparatus (JGA) is an essential structure in the regulation of renal function. The JGA embodies two major functions: tubuloglomerular feedback (TGF) and renin secretion. TGF is one of the mechanisms mediating renal autoregulation. It is initiated by an increase in tubular NaCl co...

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Bibliographic Details
Main Authors: Sophie Møller, Jens Christian Brings Jacobsen, Niels-Henrik Holstein-Rathlou, Charlotte M. Sorensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Physiology
Subjects:
gap junction
vascular conducted response
electrical pulse stimulation
renal
intercellular communication
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00961/full

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