Ineffective Erythropoiesis in β-Thalassaemia: Key Steps and Therapeutic Options by Drugs
β-thalassaemia is a rare genetic condition caused by mutations in the β-globin gene that result in severe iron-loading anaemia, maintained by a detrimental state of ineffective erythropoiesis (IE). The role of multiple mechanisms involved in the pathophysiology of the disease has been recently unrav...
Main Authors: | Filomena Longo, Andrea Piolatto, Giovanni Battista Ferrero, Antonio Piga |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/13/7229 |
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