Inhibitory Effects of <i>N</i>-[2-(4-acetyl-1-piperazinyl) phenyl]-2-(2-chlorophenoxy) acetamide on Osteoclast Differentiation In Vitro via the Downregulation of TRAF6

Inhibitory Effects of <i>N</i>-[2-(4-acetyl-1-piperazinyl) phenyl]-2-(2-chlorophenoxy) acetamide on Osteoclast Differentiation In Vitro via the Downregulation of TRAF6

Osteoclasts are poly-nuclear cells that resorb mineral components from old or damaged bone tissue. Primary mononuclear cells are activated by receptor activator of nuclear factor kappa-&#914; ligand (RANKL) and differentiate into large multinucleated cells. Dysregulation of osteoclast differenti...

Full description

Bibliographic Details
Main Authors: Zhihao Chen, Eunjin Cho, Jinkyung Lee, Sunwoo Lee, Tae-Hoon Lee
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
piperazine
osteoclastogenesis
traf6
bone resorption
Online Access:https://www.mdpi.com/1422-0067/20/20/5196

Internet

https://www.mdpi.com/1422-0067/20/20/5196

Similar Items